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Eric Topol Newsletter
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20 September
19 September
18 September
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korrents.com
The medical system that broke Adam Kay in 2010 is still producing more similarly damaged doctors, and faster.Their words
the system that broke him in 2010 is, in 2026, still producing more of him, faster.
17 September
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31 August
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Their words
That reckless expansion is particularly dangerous because it lacks an end point.
29 August
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20 August
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korrents.com
Humanoid robots paired with AI will eventually deliver medical care to everyone on Earth.Their words
One day, Optimus + Grok will provide incredible medical care to all the people of Earth
17 August
7 August
From one piece Max Hodak: Average Is Not Good Enough 2 beliefs, in the piece's order there
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Their words
It gives you these effect sizes that you just don't really see in medicine. Like if you have a patient on on a dopamineergic drug for Parkinson's that works for some period of time, but it's a it's a relatively small effect after a little while. You turn on a deep brain stimulator and a patient goes from not being able to hold a cup of water to being able to write cursive in like 10 seconds.
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Their words
I think one of the things that makes science the company very special is that it has both of those cultures and is able to integrate them and we're able to simultaneously do some really cool research that I think is really at the edge of the Overton window while simultaneously running clinical trials in six countries now with an approved medical device in Europe and clinical trial results in the New England Journal of Medicine.
3 August
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Their words
Irrigation cools the surface, and the expansion of agriculture and irrigation in the central U.S. in the middle of the 20th century played a key role in why heatwaves were low in the middle of the 20th century
29 July
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Their words
I truly believe these these models are already just incredibly powerful. Like they should they should be so powerful to fuel, you know, um many many points of expansion of GDP growth and I think it's like up to smart people with vision and ambition to make all that happen.
27 July
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Their words
I told him what I believe: that in the age of AI, medicine will be bottlenecked more than ever by regulation and the grind of clinical trials, and that billions poured into faster pre-clinical research won’t touch that problem, unsexy as it is.
Intelligence is not the main bottleneckwritingruxandrabio.com
12 July
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Their words
It is actually pretty likely that it was Google's efficiency actions that enabled their total energy consumption to increase.
27 June
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27 May
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korrents.com
Gamified learning is medicine wrapped in candy, and in practice children eat the candy and throw the medicine away.Their words
Gamified learning is a bit like wrapping medicine in candy. Yes, it may help some students swallow some instruction they otherwise find bitter, but in practice it’s easy to pull off the candy, consume it, and throw the medicine away.
20 May
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Their words
Focus on making great computers with great user experiences above all else, and you can trust that every other major goal will follow: profit, market share, expansion, impact, and benefit to the world.
29 January
From one piece How Until is Engineering Away Time in Organ Transplants | Laura Deming 2 beliefs, in the piece's order there
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Their words
but I think that the thing that a lot of people will face is just like this question of like is it worth you know traveling so far to give up my current social context and that will put a limit on like how much people want to use this for
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Their words
But right now like there's no way to press pause on their biological time. So like what if you had an ambulance of the future, right? Like what if you could take someone who is on their deathbed and um you know find some way to you know just sort of hibernate them basically until um the sort of critical cure for their disease comes online.
28 December 2025
27 November 2025
2 October 2025
22 August 2025
From one piece The Rumpelstiltskin effect: therapeutic repercussions of clinical diagnosis (with 1 co-authors) 3 beliefs, in the piece's order there
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Their words
Likewise, self-diagnosis should be understood as an attempt to secure the therapeutic effect of a medical intervention to which patients do not have official access.
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korrents.com
Diagnoses that have therapeutic effects are medical interventions and should be treated and researched as such.Their words
If a clinical diagnosis can have a therapeutic effect, then, at least in some instances, diagnoses are medical interventions in themselves and ought to be treated and researched as such, with an eye to both positive effects and potential iatrogenic harms.
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korrents.com
Clinical diagnosis can have a therapeutic effect independent of any other intervention.Their words
Their experiences highlight a striking, neglected and unchristened medical phenomenon: The therapeutic effect of a clinical diagnosis, independent of any other intervention, where clinical diagnosis refers to situating the person's experiences into a clinical category by a clinician or the patient.
18 August 2025
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Their words
I just think about like really simple things like access to mental health care, access to education, access to medical advice, access to legal advice. We're essentially taking expertise and making it a commodity. And I think that will is generally democratizing.
2 August 2025
From one piece What does AI progress mean for medical progress? 2 beliefs, in the piece's order there
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Their words
Rapid AI progress does not automatically mean rapid medical progress. If the point of AI progress is human flourishing, we must make other complementary investments too.
What does AI progress mean for medical progress?blog.jacobtrefethen.com
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korrents.com
Not every bottleneck on medical progress is one AI can remove, and which ones will remain can be guessed at now.Their words
But I don’t think all bottlenecks on medical progress are equally AI-able in the next decade, and I don’t think all will become irrelevant.
What does AI progress mean for medical progress?blog.jacobtrefethen.com
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Their words
Some models could be used both for good and ill, yes. Diffusion models in particular could be used by bad actors to hallucinate toxins or other harmful proteins.
AI could help lead to an Alzheimer's cureblog.jacobtrefethen.com
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Those are why I do not believe that AI could end disease within 10 years on its own, nor that 50-100 years of medical progress could occur 5-10 years after powerful AI due to AI progress alone
AI will not suddenly lead to an Alzheimer's cureblog.jacobtrefethen.com
14 June 2025
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21 April 2025
9 December 2024
28 October 2024
1 October 2024
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korrents.com
Powerful AI will compress the biological and medical progress of the next 50-100 years into 5-10 years.Their words
To summarize the above, my basic prediction is that AI-enabled biology and medicine will allow us to compress the progress that human biologists would have achieved over the next 50-100 years into 5-10 years.
8 July 2024
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From the onset, I envisioned small firms of professional maintainers with thematic portfolios, accommodating diverse maintainers and project sizes, just like the specialized firms of other professionals.
2 June 2024
8 May 2024
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Their words
Our experiment demonstrates that the immense potential benefits of biotechnology are profoundly vulnerable to misuse.
13 March 2024
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Their words
Without yield improvements, therefore, we would have seen more than double the cropland expansion.
23 December 2023
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Their words
Biology is unpredictable, especially when the immune system is involved, and there is no guarantee that a drug that appears safe in animals will be safe in humans.
17 November 2023
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korrents.com
NATO expansion into Ukraine was the principal cause of the war, which makes the West principally responsible for it.Their words
And of course, what they were negotiating about was NATO expansion into Ukraine, which was the principal cause of the war. People in the West don't want to hear that argument because if it is true, which it is, then the West is principally responsible for this bloodbath that's now taking place.
3 November 2022
14 June 2022
1 June 2022
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Their words
If a fiscal expansion takes place when output is already at potential, monetary policy is likely to tighten, leading to higher interest rates and thus a smaller effect or even no effect of the fiscal expansion on output.
22 November 2021
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Likedaffiliate linkrcmnd.app
Extra LifeTheir words
Steven Johnson, Extra Life – Johnson explores the astonishing expansion in life expectancy over the last two hundred years, and asks how we measure it and who – and what – deserves the credit. Wide ranging and a pleasure to read.
22 June 2020
4 June 2020
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korrents.com
Plague receded from Europe through fourteen generations of natural selection, not through any advance in medicine.Their words
when plague finally diminished in Europe, not because of any advance in medicine, but because fourteen generations of exposure gave natural selection time to work
28 January 2020
26 July 2019
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Human error is blamed for over 90 percent of industrial and automobile accidents. It is the leading cause of aviation accidents, and medical error is reported to be the third-largest cause of death in the entire United States. Horrifying? Yes, but why do we label it “human error”? It is design error.
21 January 2019
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korrents.com
Formal methods are not standard practice even in high-assurance software such as medical devices and aircraft.Their words
most people in high-assurance software don't use formal methods
16 April 2018
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Lovedrcmnd.app
A Fortunate Man: The Story of a Country DoctorTheir words
The book becomes an extended meditation on the practice of medicine, which is an attempt to engage a deep sense of fraternity.
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Recommendsrcmnd.app
Hippocratic WritingsTheir words
So right there at the beginning, before there was even a profession such as medicine, there is some writing with a scientific appreciation of the body and how to make it better. There's no dogma here, because they're constantly asking, try this for yourself, prove me wrong! And there is also the beginning of a professional ethic about a group of people who should hold each other to high moral and clinical standards. A few of the writings complain about quacks, who rip people off, and don't pay attention to the high standards.
27 July 2017
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