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17 September
British open-standards and open-source technologist, formerly of the UK Government Digital Service and the W3C Advisory Committee. Blogs at shkspr.mobi, where he posts a book review most weeks.
@drstevex.bsky.social may I introduce you to @hayleygullen.com who wrote a brilliant and funny graphic novel about cancer? She'd be excellent for your medicine event. Related
16 September
Deep-learning researcher and Turing Award laureate; founder of the Mila institute.
Bluesky I am very proud of what the team at @law-zero.bsky.social is building and deeply grateful for the landmark support from the Governments of Canada and Germany that will power our next phase of growth! Quoting @law-zero.bsky.social We are happy to share that Canada and Germany have announced funding of up to $300 million for LawZero! This will power the next phase of our technical roadmap towards developing a fundamentally new form of advanced, safe, and capable AI. lawzero.org/en/news/lawz... Related
x.com I am very proud of what the team at @LawZero_ is building and deeply grateful for the landmark support from the Governments of Canada and Germany that will power our next phase of growth! Quoting @LawZero_ We are happy to share that Canada and Germany have announced funding of up to $300 million for LawZero! This will power the next phase of our technical roadmap towards developing a fundamentally new form of advanced, safe, and capable AI. Related
14 September
Physician focused on longevity; wrote Outlive and hosts The Drive.
12 September
Investor and writer. Previously a partner at Andreessen Horowitz and a product leader at Twitter, Facebook, Snap and Microsoft. Writes essays and memos at sriramk.com.
I find myself disagreeing with Terence Tao (a very scary phrase to say!) and think the core question posed is whether the "misalignment" is between the mathematical community and humanity. In other words - are the Millenium Prize problems meant to incentivize advancements for humanity or foster the field of mathematics and mathematicians? As a counter example, if there was a prize for creating a drug that cured a rare strain of cancer, we would not care if it was AI that did it. We would be happy it has been solved. On the other hand, if long running agents figured out the puzzle in "Kryptos"… AI alignment Related
Former option trader and risk analyst, now a distinguished professor at NYU. Author of the Incerto essay series, including The Black Swan and Fooled by Randomness.
If AI mapped a cure for terminal pancreatic cancer I don't think anyone would dare complain about its effects on medical unemployment. But people are upset that AI can solve math problems and cause unemployment in performative mathematics. Fuck them. AI and jobs Related
Mathematicians rank problems according to their difficulty. Society looks at them in terms of relevance. I've fought that cancer in mathematical finance where these retards ignore v. relevant issues, some critical, because they deem them trivial. Let AI wipe them out. Quoting @nntaleb Something bad for the (existing) class of mathematicians as they lose their privilege, but not necessarily bad for mathematics & our body of knowledge? Related
9 September
Canadian software developer and writer, co-editor of the XML and Atom specifications and formerly of Sun Microsystems, Google and AWS. Has written the blog ongoing since 2003.
@anildash has written a few pieces about “cancer” capital recently, and his most recent, “Cancer Capital: It Sucks For Founders, Too!” gets specific about malfeasance: https://www.anildash.com/2026/09/09/cancer-capital-founders/ Also: Hey Anil, could you relax the kerning on that big-outline title font? It’s so tight it looks like it’s going to explode and shred my face. #venturecapital startups Related
7 September
British historian, translator and broadcaster; author of Rubicon and Dominion, and co-host of The Rest Is History podcast.
I guess a church that compromises a sense of itself as a sacred space does indeed risk diminishing itself to the status of a landmark. Quoting @MayorofLondon Fabric. St Paul’s Cathedral. Name a more iconic duo. Bringing together these two institutions will create a one-of-a-kind experience, pairing world-class music with one of our most special landmarks. Related
Creator of the Keras deep-learning library and the ARC-AGI benchmark.
AGI energy
Their words
The narrative around why building AGI was a good idea has always been about invention -- "it will cure cancer", "it will solve fusion energy", etc.
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@fchollet on X x.com
3 September
CEO of SafeGraph, host of the World of DaaS podcast, and author of the Summation newsletter; previously founded LiveRamp.
more and more software will be n of 1. We recently invested in a company that is doing an n of 1 cancer treatment. They are creating a cancer drug that will only work for one very very specific person and will be essentially useless for every other person. The n of 1 way of thinking is going to pervade everything that we do. More and more software that's being written is n of 1. It's going to be useful for just one person or useful to just one organization and have almost no use at all to anyone else. Yet it will be just extraordinarily useful for that one person, just like the cancer drug. n… Related
American software engineer; worked on code-server at Coder and teaches TypeScript and open-source contribution. Publishes at joeprevite.com.
there is no better way to improve a business than dogfooding yourself which means treating myself as a client for the wellness coaching main problem i've been trying to help myself with mouth-breathing at night. things i've tried so far: - nasal rinse (tiny bit of salt + baking soda) - coconut oil in nostrils - humidifier and i think i've finally figured out what's going on... current theory is retainer is preventing me from forming a good "lip seal" (upper retainer pushing upper lip up, keeping mouth open) so next week's a/b experiment is to try sleeping without retainer and take notes Related
1 September
Genomics researcher and writer on science, biotech and the culture of research.
30 August
Cardiologist and founder of the Scripps Research Translational Institute; writes Ground Truths on biomedical research, and wrote Super Agers and Deep Medicine.
29 August
Founder and CEO of Social Capital, a venture firm; co-host of the All-In podcast and an early Facebook executive. Writes an annual letter and a weekly newsletter on markets and technology.
28 August
Zurich-based value investor who ran the Aquamarine Fund from 1997 to 2025 and wrote The Education of a Value Investor. He hosts the VALUEx gathering in Klosters and publishes a podcast and newsletter.
I'm in a clinical trial for a brain cancer vaccine. Last month I sat down with the two men who invented it. Michael Ciesielski and Robert Fenstermaker. The idea is a vaccine called SurVaxM. It teaches the immune system to recognise survivin, a protein that helps cancer cells refuse to die. Glioblastoma is full of it. Fifteen years to get it from a Buffalo lab into patients. Related
26 August
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
x.com I wrote about the Moderna melanoma cancer vaccine news briefly for our weekly round up Related
Bluesky I wrote about the Moderna cancer vaccine news briefly for our weekly round up abundanceandgrowth.org
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22 August
Belgian engineering lead, Microsoft MVP and public speaker. Creator of Front Matter, a headless CMS extension for Visual Studio Code.
Tore a hole in my tire on a bump today. Only thing on hand: a sticker I made for Yves. Stuck it inside the tire and rode home on it. Yves died last year from cancer. Today his sticker saved my ride. Weirdest place I ever pictured one of his stickers ending up. 💫 🚴♂️⚡ Related
Co-founder of Y Combinator and Viaweb; essayist at paulgraham.com.
data centers America
Their words
Preventing companies from building data centers in America wouldn't slow down the rate of progress in AI. It would merely slow down the rate of progress in AI in America.
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@paulg on X x.com
20 August
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
(Almost) everything you'd want to know about cancer vaccines can be heard in this great @owl_posting podcast episode from June, feat @iskander @BenjaminGVincen. Highly recommended! owlposting.com
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12 August
Cardiologist and founder of the Scripps Research Translational Institute; writes Ground Truths on biomedical research, and wrote Super Agers and Deep Medicine.
4 August
Cardiologist and founder of the Scripps Research Translational Institute; writes Ground Truths on biomedical research, and wrote Super Agers and Deep Medicine.
29 July
Professor of atmospheric sciences at Texas A&M; writes The Climate Brink with Zeke Hausfather.
20 July
Physician and neuroscientist at the University of Washington; researches brain health, metabolism and athletic performance.
Trauma
Their words
So there have been lots of studies where they've done cooling hypothermia in people after traumatic brain injuries and concussions hasn't really shown much of an effect. What seems to be important is preventing hyperothermia.
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youtube.com
17 July
Climate journalist; founded HEATED in 2019 after reporting on climate at The New Republic and ThinkProgress.
4 July
Physician focused on longevity; wrote Outlive and hosts The Drive.
3 July
Cardiologist and founder of the Scripps Research Translational Institute; writes Ground Truths on biomedical research, and wrote Super Agers and Deep Medicine.
14 June
Writes Nintil, long researched essays on metascience, biology, economics and whatever he has decided to read the literature on.
13 June
Cardiologist and founder of the Scripps Research Translational Institute; writes Ground Truths on biomedical research, and wrote Super Agers and Deep Medicine.
10 June
Co-founder and chief executive of Meta Platforms, the company he started as Facebook in 2004.
Their words
But still, I thought that by the end of the century was a stretch. Now, I think it's like uh too conservative.
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youtube.com
9 June
Historian of maritime strategy at the US Naval War College; wrote The Wars for Asia and works on why continental and maritime powers fight differently.
From one piece
Sarah Paine - Why Putin and Xi can't escape geography
2 beliefs, in the piece's order there
Their words
But the maritime world is about negative objectives. It's preventing things from bad things from happening. And um you can never prove that you prevented anything.
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youtube.com
Their words
Sanctions are like economic chemotherapy. What you're doing is presenting preventing one or two percent growth per annum even with leaky sanctions, right?
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youtube.com
30 May
Emeritus Professor of Statistics at the University of Cambridge, former president of the Royal Statistical Society, and author of The Art of Statistics.
https://t.co/b8OEpYqvYT This seems a predictable failure, as 2021 data showed the test only picked up 28% of Stage 1/2 cancers. How much did this study of 140,000 patients cost? And the list price for detecting one cancer using GRAIL is $200,000 - was it ever feasible for NHS? Related
27 May
Investing columnist for The Wall Street Journal and editor of the revised edition of Benjamin Graham's The Intelligent Investor.
I joined @JeanChatzky on the @HerMoneyMedia podcast to honor my dear friend, the late @ClementsMoney, and his final book, "Money and Me." We talked about: * why his simple, sound investing philosophy still endures * what his terminal-cancer diagnosis taught him about the meaning of money * why the shift from saving to spending in retirement is so psychologically difficult * what Jonathan's final year, spent eating good food with good friends, can teach us all about living well Listen here: lnk.to
Related
26 May
Pseudonymous writer; posts careful, funny investigations of everyday questions — air quality, seed oils, arguing, chess — usually by reading the studies.
3 May
Writes Nintil, long researched essays on metascience, biology, economics and whatever he has decided to read the literature on.
There was only mom One morning I got a call from my younger brother Jaime. He was crying. He tells me my mom’s health, which had been slowly declining over the past month from advanced cancer, had reached the point where not much time was…
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1 May
Freelance climate and energy analyst in Oslo, writing on Europe, the US and Australia; worked in the Australian renewables industry before that.
Their words
The only solution is preventing the disease, not treating the symptoms.
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ketanjoshi.co
13 April
Data scientist at Our World in Data and author of Not the End of the World. Writes By the Numbers, working through energy and climate questions with the numbers in front of them, and revising in public when they say something unexpected.
15 March
Genomics researcher and writer on science, biotech and the culture of research.
13 February
Co-founder and CEO of Anthropic; previously VP of research at OpenAI.
Their words
There's There's nothing preventing longer context from working. You just have to train at longer context and then learn to to serve them at inference. And both of those are engineering problems that we are working on and that I would assume others are working on as well.
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youtube.com
21 January
Swiss full-stack developer working mostly with Laravel and Vue; author of the widely used git-auto-commit-action GitHub Action.
Man. What a week! Started on a high on the weekend with doing good progress on a secret project and on Monday at work as well. Tuesday, still good progress but also had a quick shocker as a friend didn't answer their phone for 3 hours and we thought something happened to them. And today started with getting the notice that a friend from the local gym died after their cancer returned. 😭 And the whole world politics definitely starts to pull me down more and more. Can't wait for Saturday! Related
18 January
Genomics researcher and investor; writes The Century of Biology on where biotechnology is actually going.
17 January
Emeritus Professor of Statistics at the University of Cambridge, former president of the Royal Statistical Society, and author of The Art of Statistics.
https://t.co/ENzer2fHqJ I will be saving £250 a month in future, as Abi helps keep my locally advanced prostate cancer under control. I can afford it, but absurd it's taken so long for NHS to pay for this very effective drug. Hats off to campaigners and @BBCHughPym for coverage Related
24 December 2025
Writes Nintil, long researched essays on metascience, biology, economics and whatever he has decided to read the literature on.
27 October 2025
Writes Nintil, long researched essays on metascience, biology, economics and whatever he has decided to read the literature on.
15 August 2025
Founder of Terraform Industries and formerly a physicist at NASA's Jet Propulsion Laboratory; writes about energy, space and manufacturing.
energy China America
Their words
In terms of things that are causing us to lose to China, tariffs are neither here nor there because, as we've discussed, we're not sensitive to cost on power. But the environmental regulations that are actively preventing us from deploying renewable energy in the United States, like this is the reason Texas is winning. Texas is out deploying California 10 to1.
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youtube.com
13 August 2025
Economist specialising in China's economy, international macroeconomics and global trade, and author of The New China Playbook.
China America
Their words
And remember that DeepSeek happened in times of crisis, urgency, not in times of comfort. A lot of these technological breakthroughs and leapfrogging happens in times of crisis. This is called crisis innovation. And you got to thank the US for that. When the Chinese were comfortably importing chips from the US, the whole industry stalled for 20 years.
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youtube.com
3 August 2025
Philosopher at Oxford; co-founded effective altruism and 80,000 Hours, wrote Doing Good Better and What We Owe the Future, and now works on what a good future would actually contain.
2 August 2025
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
22 June 2025
Computer science professor at Georgetown University and author of Deep Work, Digital Minimalism and Slow Productivity; writes about focus, technology and work at calnewport.com and hosts the Deep Questions podcast.
24 April 2025
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
Their words
In my view, without smoking, we probably would have seen cancer mortality decline much earlier.
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scientificdiscovery.dev
20 April 2025
Genomics researcher and writer on science, biotech and the culture of research.
5 April 2025
Director of strategy at Georgetown's Center for Security and Emerging Technology; an OpenAI board member until November 2023, and writes Rising Tide.
Their words
The current status quo—where new models that push the frontier are kept private, and openly available equivalents are only released after a lag of months or years—is valuable.
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helentoner.substack.com
11 March 2025
Independent AI policy researcher; led policy research at OpenAI from 2018 to 2024, latterly as senior adviser for AGI readiness.
21 January 2025
Mathematical biologist; Senior Lecturer in the Department of Mathematical Sciences at the University of Bath and author of The Maths of Life and Death and How to Expect the Unexpected.
10 January 2025
Independent AI policy researcher; led policy research at OpenAI from 2018 to 2024, latterly as senior adviser for AGI readiness.
23 December 2023
Writes about the biotech industry, drug development and forecasting — “I write to learn, mostly about biotech.”
Their words
The most significant factor preventing us from taking better molecules into clinical trials is not our ability to design arbitrary molecules, but our (lack of) understanding of underlying disease biology. In other words, we often know how to make something, but not what to make.
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atelfo.github.io
3 November 2023
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
24 January 2023
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
7 April 2022
Programmer and entrepreneur; co-founded GitHub and created Jekyll, Gravatar and the Semantic Versioning spec.
20 July 2021
Cryptographer; teaches cryptography at Johns Hopkins and writes A Few Thoughts on Cryptographic Engineering.
21 June 2021
Emeritus Professor of Statistics at the University of Cambridge, former president of the Royal Statistical Society, and author of The Art of Statistics.
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What is a korrent?
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