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Jamie Brandon GitHub
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18 September
16 September
15 September
12 September
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Their words
the more that we see actors looking to weaponize without any very good maps of how and what they are doing or what kinds of unexpected repercussions might happen, the more we can expect not simply increased risks of tension and worry, but also people screwing up, doing dumb stuff.
11 September
9 September
8 September
6 September
5 September
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Their words
We can’t count on surrogate blood markers to guide the results of cardiovascular clinical outcome trials.
The Coronary Artery Inflammation Controversyerictopol.substack.com
4 September
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Their words
There is also a very important step called randomization. Is that you have to take the same environment and then randomize the conditions. So, the cable doesn't literally only, you know, uh bend this way. It can bend a different way or the box can have different sizes, colors, different lids, and all that.
31 August
29 August
28 August
25 August
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Their words
The problem is that "number of recalls" is a terrible metric because we don't know what we don't know.
18 August
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Their words
I think it's all about having regulatory clarity and ease for all sizes of of companies. Um and if we can work with Congress to do something like that, I think that would be that would be the biggest boon for for for startups.
17 August
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Their words
it's ultimately about people's concepts of how emotions correspond to changes in the body, not the real actual changes in the body.
15 August
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Their words
Nuclear energy is the safest form of energy empirically. If you look at the amount of power generated versus the amount amount of deaths, um it's even safer than solar, which is very strange because how does someone die from solar? that actually most solar is installed on roofs and people sometimes die falling off of a roof installing solar and if you add those deaths up it is actually a higher death per energy than the totality of nuclear energy in the world.
14 August
12 August
10 August
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Their words
If you count all the permutations, you can write all the tests you want. It is impossible to cover all of these and not break things from time to time. It is infinitely harder to evolve software that has users.
9 August
7 August
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Their words
It gives you these effect sizes that you just don't really see in medicine. Like if you have a patient on on a dopamineergic drug for Parkinson's that works for some period of time, but it's a it's a relatively small effect after a little while. You turn on a deep brain stimulator and a patient goes from not being able to hold a cup of water to being able to write cursive in like 10 seconds.
2 August
From one piece This CPO regrets that product management exists | Tom Verrilli (CPO of Whatnot) 2 beliefs, in the piece's order there
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Their words
there are people who are really big on road maps and there are people who are really big on iteration. I I think the honest answer is you've got to do both. You can't over-index on either.
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Their words
commerce has totally different economics to entertainment and CPMs aren't the thing that you have to worry about.
27 July
20 July
8 July
9 June
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Their words
And then for those of you who are skeptical about international organizations, here's one you've never heard of. The International Organization for Standardization then standardized these container sizes to fit one if by truck, two if by railway cars, and thousands if by sea. And this just plummets transport costs.
19 May
13 May
8 May
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Their words
But, what's not been successful is learning about uh biology and biological change. And one big reason for that has been that the sample sizes have been too small.
5 May
30 April
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19 April
15 April
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Their words
Pick your ASIC team where you can say I can bet the farm of I can bet my entire business that you will be here for me every single year. Your cost, your token cost will decrease by an order of magnitude every single year. I can count on it like I can count on the clock.
7 April
20 March
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Their words
you know, right now we're going through uh an in um an cognitive version of the Copernican revolution where we used to think that human intelligence is the center of the universe. And now we're actually seeing that there's there's very different types of intelligence um that that that are out there uh with very different strengths and weaknesses.
11 March
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korrents.com
Nobody will believe a resume any more; what will count is visible proof of the work you actually did.Their words
we are moving into a world very quickly this year where proof of work is so important and I mean proof of work not in the Bitcoin sense but your proof of what you have done, your resume. And I don't mean your resume because nobody's going to believe that. I mean the actual work that you did which has to be visible
18 February
12 February
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Their words
If you get really good at coding that means you have to be really good at general purpose problem solving. So that's a skill, right? And that just maps into other domains.
9 February
30 January
5 January
1 January
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Their words
But you cannot outwork the person who's working on a better thing. And so um it is possible if you really grind maybe you can work 10% harder or 20% harder than you are now. But if you work on the right thing you get 100x of the results or thousandx the results. And so what you need I I almost feel like we should change the definition of what it means to work hard. It should not only mean putting in the hours. It should also mean outthinking the other person.
13 December 2025
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Dislikedrcmnd.app
Google MapsTheir words
Google Maps essentially really doesn't work in China, the location of our hotel Aman in Beijing for example was completely wrong
21 September 2025
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Their words
used to be let's say in the Google world right I knew you were interested in shopping if you click the shopping tab I know you're interested in maps if you click the maps tab, we can measure clicks. Today, it's just all conversation. And so, it's actually harder for us to tease apart what is the user intent.
24 July 2025
26 December 2024
30 September 2024
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Their words
I mean, if that’s right, that means the Maya and the people of Mesoamerica will all share it together, when they thought about, “We need a count of time for us,” they didn’t look up into the heavens, they looked into their bodies. “What’s the first cycle that we actually go through as humans?” and they picked this nine-month thing. It really is our cycle, and no other culture on the planet looked inside themselves to create their calendar like that.
21 August 2024
8 July 2024
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Their words
From the onset, I envisioned small firms of professional maintainers with thematic portfolios, accommodating diverse maintainers and project sizes, just like the specialized firms of other professionals.
7 May 2024
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Their words
So when evaluating control, we should count catching an AI red-handed as a win condition.
18 April 2024
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korrents.com
A data centre powered by solar and batteries alone needs an array so oversized that the design is not worth building.Their words
The solar array sizes under these assumptions are prohibitively large.
How to Make Off Grid Data Centers Affordableaustinvernon.site
22 March 2024
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Their words
So you don’t have wise decision makers. Long gone are the days where we had presidents who had advisors on both sides of the aisle. That’s really important, because you want to have differing opinions. But as things become more viperous, both here in the United States and in nuclear armed nations, all bets are off at whether your advisors are going to give you good advice.
12 February 2024
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korrents.com
Large research team sizes on frontier AI projects create friction that makes execution and decision-making harder.Their words
Such size poses challenges for the effective execution and prioritization, increasing friction and making it more difficult to quickly make decisions.
30 January 2024
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Their words
I think that the enshittification framework goes a long way to explaining it, moving us out of the mysterious realm of the 'great forces of history,' and into the material world of specific decisions made by named people – decisions we can reverse and people whose addresses and pitchfork sizes we can learn.
1 October 2023
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Their words
It is a sign that Hayek was not so great at seeing the viewpoints of other people, and that (political moralizing aside) also should count as a weakness of him as an economist and social scientist.
21 September 2023
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korrents.com
Grinders that produce fewer fines (more unimodal) also tend to produce more uniform particle sizes.Their words
Contrary to popular hearsay, more unimodal grinders appear to also be more uniform on average.
1 September 2023
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Their words
So if you can predict it doesn't count as emergence, actually.
24 January 2023
27 December 2022
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korrents.com
Compressing a piece of research into a journal paper's word count is itself a distortion of what was found.Their words
The mere act of squeezing a complex process into a few thousand words—limited by a journal-imposed word count—is itself a distortion of reality.
13 December 2022
From one piece The rise and fall of peer review 2 beliefs, in the piece's order there
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Their words
Scientists have run studies where they deliberately add errors to papers, send them out to reviewers, and simply count how many errors the reviewers catch. Reviewers are pretty awful at this.
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Their words
Making peer review harsher would also exacerbate the worst problem of all: just knowing that your ideas won’t count for anything unless peer reviewers like them makes you worse at thinking.
5 November 2022
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Their words
All radically new products, and air taxi eVTOLs certainly count as radically new, require the convergence of many different capabilities and technologies. Often one or more technology will be lagging and it may take decades for them all to come together in the right place at the right time.
11 October 2022
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korrents.com
Published effect sizes shrink as more studies are done, and that decline is what the replication crisis is made of.Their words
The decline effect is the idea that scientific findings get smaller over time. That is, initial findings tend to report effect sizes that then crumble away—sometimes to nothing—with subsequent research.
20 September 2022
30 June 2018
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Recommendstheir ownrcmnd.app
World Atlas of WineTheir words
The World Atlas of Wine has unrivalled maps. Hugh did a fantastic job, the real spadework, of getting some top quality maps of the world's classic wine regions and many of the new ones. The original editions had Hugh's matchless prose, trying to encapsulate the spirit of each region in surrounding texts, but the maps are the thing, and some photographs.
13 April 2018
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