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19 September
Physician focused on longevity; wrote Outlive and hosts The Drive.
18 September
Entrepreneur and founder of Blueprint. Publishes a detailed, freely available longevity protocol documenting the food, supplements, devices and measurements he uses on himself.
Old female mice on semaglutide lived 12% longer and ran 2.8× as long before exhaustion. Other gains: > treadmill time to exhaustion +177% > hanging time +124% > rotating-rod performance +47% > open-field movement +50% > glucose tolerance: area under the curve −20% > Improved spatial memory: maze escape time −57% > reduced inflammation -55% > reduced senescence -65% > stem cell rejuvenation: hippocampal neurons ~3x > bone marrow colonies +44% > DNA damage & stress -44% Treatment started at 20 months of age (human equivalent to 60s). Control was a separate group of mice on a 24% food restrictio… Related
16 September
Analyst of the business of technology; writes Asymco on Apple, disruption and, latterly, micromobility.
What happens when smartphones become too good? Thoughts just before the Duo launched The smartphone industry has spent much of its history persuading consumers that the device in their pocket could be substantially better. Cameras improved, screens sharpened, and mo…
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CEO of Positive Sum and founder of Colossus. Hosts Invest Like the Best, interviewing investors and business leaders; the guests do most of the talking there.
Despite being widely regarded as one of the best venture investors of all time, Michael Moritz says he's never once felt like he was good at something: "I've never felt I'm really good at something. That's not false modesty on my part. Everybody is plagued by doubts and competitiveness. And it's a failing on my part. I have a very difficult time celebrating good things and celebrating success. I think I've always felt everything is unfinished and could be improved. None of it's ever been perfect. Sometimes when I paint and compare a painting to what I might have been able to paint 10 years ag… Quoting @patrick_oshag My conversation with Michael Moritz, one of the great venture investors of the last 40 years. Michael joined Sequoia in 1986 and co-led the firm with Doug Leone (@dougleone) from 1995 to 2012. His investments include Google, Yahoo, PayPal, and Stripe. His new book, Ausländer, traces his parents' es… Related
13 September
Moroccan senior frontend developer writing at smakosh.com; builds side projects and client work under Smakosh LLC.
Connectors improved on The Lounge by @llmgateway More will be enabled and more to be added Related
Token breakdown improved on the analytics page on @llmgateway Related
Psychologist and writer. Author of the memoir Troubled: A Memoir of Foster Care, Family, and Social Class, and of a newsletter on human nature, psychology, social class and what he calls luxury beliefs.
Their words
The deniers of free will haven't improved society. They have merely produced a more forgiving vocabulary for those who damage it.
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robkhenderson.com
10 September
Writes The Diff, a newsletter on inflections in finance and tech read by hedge fund managers, founders and VCs. Previously worked in finance at SAC Capital/Point72.
One of the kids got a surprisingly bad grade on a spelling pre-test, so I gave Codex a picture of the test and told it to build a practice app. Much improved! Related
2 September
Canadian cartoonist and writer: Dinosaur Comics, Marvel's The Unbeatable Squirrel Girl, and the choose-your-own-path books To Be or Not To Be and Romeo and/or Juliet.
31 August
Usability pioneer; co-founder of Nielsen Norman Group and founder of UX Tigers; author of the ten usability heuristics and of Jakob's Law.
26 August
Programmer; makes Handmade Hero and teaches Performance-Aware Programming, and argues loudly about how software got slow.
Their words
What is the underlying hardware capable of doing at its theoretical peak? And then you measure the delta between that theoretical maximum and what you have achieved.
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youtube.com
6 August
Short-story writer and novelist; won the Booker Prize for Lincoln in the Bardo, and teaches craft weekly in Story Club.
13 July
Professor of psychology at UCLA, where he studies human memory, attention and cognitive ageing, and author of Better with Age: The Psychology of Successful Aging.
Their words
I think some research, again it's correlational, shows that people who spend, you know, 5 hours a week with their grandchildren have improved memory. So that seems we don't know if it's causal, but it's interesting that those who spend more than 20 hours a week don't show this benefit. In fact, might show the opposite.
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youtube.com
9 July
Labour politician. Prime Minister of the United Kingdom from July 2024 to June 2026, and MP for Holborn and St Pancras from 2015 until standing down in 2026. Director of Public Prosecutions before entering Parliament.
I promised that we would fix our NHS, so it’s fit for the future. Today, more patients are reporting improved experiences with their GP, dentist, and pharmacist since we’ve been in government. Delivering real change to people across the country. government Related
19 June
Writer and climate campaigner; wrote The End of Nature in 1989, founded 350.org and Third Act, and writes The Crucial Years.
5 June
Economist; Professor of the Practice of Economic Policy at Harvard, nonresident senior fellow at the Peterson Institute, and Chairman of the US Council of Economic Advisers from 2013 to 2017.
Another strong month for job growth. 172K in May with upward revisions for previous months that brings the three month average to 188K. Unemployment rate stable at 4.3% while broader measures (U-6 and employment rate) both improved. AI and jobs Related
28 May
Writer on learning and skill acquisition; author of Ultralearning and Get Better at Anything, known for the MIT Challenge and the Year Without English.
New Article Why I’m Skeptical About Efforts to Revolutionize Schooling https://t.co/vHwneQy2rU I still believe learning can be improved dramatically for motivated people. But I’ve become much less optimistic about simple solutions for fixing education at scale. Related
9 May
Writer and consultant on technology, organizations and history; founded the blog Ribbonfarm and now writes the Contraptions newsletter.
Ribbonfarm has been resurrected as a museum blog with an AI curator. Details: https://t.co/InHymQ7kS3 The old reading experience is preserved intact, with significantly improved speed and cleaner reading layout, but there’s now a lot more intelligent scaffolding for exploring. Related
15 April
Co-founder of NVIDIA and, as of 2026, its chief executive; the company designs the GPUs most large AI models are trained on.
4 April
Founding member of OpenAI and former director of AI at Tesla; creator of nanoGPT and the term "vibe coding".
Wow, this tweet went very viral! I wanted share a possibly slightly improved version of the tweet in an "idea file". The idea of the idea file is that in this era of LLM agents, there is less of a point/need of sharing the specific code/app, you just share the idea, then the other person's agent customizes & builds it for your specific needs. So here's the idea in a gist format: https://t.co/NlAfEJjtJV You can give this to your agent and it can build you your own LLM wiki and guide you on how to use it etc. It's intentionally kept a little bit abstract/vague because there are so many directio… Quoting @karpathy LLM Knowledge Bases Something I'm finding very useful recently: using LLMs to build personal knowledge bases for various topics of research interest. In this way, a large fraction of my recent token throughput is going less into manipulating code, and more into manipulating knowledge (stored as mar… LLMs Related
22 March
American front-end engineer and design-systems specialist; built the Pantsuit design system for Hillary for America and has worked at Slack and IBM.
Been weird (i.e. neurodivergent) my whole life, and it improved immensely when I stopped trying to explain myself to people who are determined to misunderstand me. Quoting @smashfizzle.bsky.social If you’re a “weird” or “othered” Black Girl, the best advice I can give you is not to argue with people who have not had that experience about your experience. They will not get it, they will not try to, and your frustration won’t lead to understanding or peace. You know who you are. That’s enough. Related
20 March
Founding member of OpenAI and former director of AI at Tesla; creator of nanoGPT and the term "vibe coding".
Their words
So even though the models have improved tremendously and if you give them an agentic task, they will just go for hours and move mountains for you. And then you ask for like a joke and it has a stupid joke. It's crappy joke from five years ago and it's because it's outside of the it's outside of the RL.
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youtube.com
8 February
Software engineer; co-founder and former CTO of Tailscale, previously on the Go team at Google.
Eight more months of agents 2026-02-08 I wrote up my experiences programming with LLMs a bit over a year ago, and updated it for the world of agents eight months ago. A lot has changed since then, so here is an update. Agents have improved dramati…
LLMs Related
24 January
AI research engineer working on large language models. He writes the Ahead of AI newsletter and is the author of Build a Large Language Model (From Scratch).
6 January
Partner at Collaborative Fund and author of The Psychology of Money, Same As Ever and The Art of Spending Money. Writes essays on investor behavior and posts frequently on X.
1 January
Writer on habits and decision-making; author of Atomic Habits and the 3-2-1 newsletter, and publisher of long-running book recommendation lists.
Long-time Debian developer and free-software maintainer (remctl, INN, pam-krb5) who has published book reviews on his personal site since the 1990s.
Their words
The best book I read this year was also the last book I reviewed (and yes, I snuck the review under the wire for that reason): Bethany Jacobs's This Brutal Moon, the conclusion of the Kindom Trilogy that started with These Burning Stars. I thought the first two books of the series were interesting but flawed, but the conclusion blew me away and improved the entire trilogy in retrospect. Like all books I rate 10 out of 10, I'm sure a large part of my reaction is idiosyncratic, but two friends of mine also loved the conclusion so it's not just me.
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eyrie.org
12 October 2025
Indian technology consultant and writer. Former editor of Beautiful Pixels; writes about Apple hardware and Mac software at nuclearbits.com.
Their words
It makes for an excellent on-the-go powerhouse and I absolutely love how my video render times have improved on it.
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nuclearbits.com
22 September 2025
Indian software engineer and co-founder of Skcript; builds web apps and writes at varunraj.in.
7 July 2025
Software engineer working on distributed systems and databases; creator of rqlite, the distributed database built on SQLite.
rqlite, the lightweight distributed database build on SQLite, now supporting automatic backup-and-restore to Google Cloud Storage. Improved Disaster Recovery options. philipotoole.com
Google SQLite Related
9 June 2025
Irish independent game developer, maker of VVVVVV, Super Hexagon and Dicey Dungeons.
Just released a v1.1 patch for my Other Games. Things are feeling pretty stable, so this might be the last one? Highlights are: it shows a pop-up on itch for achievements now, it has improved accessibility options, and I added Japanese and LATAM Spanish localisations: terrycavanagh.itch.io
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18 May 2025
Member of technical staff at Anthropic. He has led ML/AI teams at Amazon, Alibaba and Lazada, and writes about LLMs, recommender systems and engineering at eugeneyan.com.
Had a fun couple of hours this weekend with Codex & Windsurf • Migrated off deprecated jekyll-algolia to official sdk (better indexing) • Added recommendations + relevance scores to each post • Improved site responsiveness; fixed dark mode flicker • Marie Kondo-ed unused files & dead code Related
8 November 2024
Alignment researcher at Anthropic; co-led OpenAI's superalignment team until 2024, and writes Musings on the Alignment Problem.
14 October 2024
Co-founder of WordPress and founder of Automattic; blogs at ma.tt.
Their words
If WP Engine didn’t want this to happen, they should not have published their code under the GPL or distributed it through WordPress.org’s directory.
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Response to DHH ma.tt
24 September 2024
Software engineer working on distributed systems and databases; creator of rqlite, the distributed database built on SQLite.
rqlite -- the lightweight, user-friendly distributed database built on #SQLite, Raft consensus and @golang -- rqlite 8.31 is out now with improved support for BLOB data. SQLite Related
7 July 2024
Professor at Carnegie Mellon working on self-driving-car safety; writes Safe Autonomy on how autonomous vehicles are and are not shown to be safe.
23 December 2023
Writes about the biotech industry, drug development and forecasting — “I write to learn, mostly about biotech.”
Their words
The cost to discover and develop a drug today is orders of magnitude higher than in the 1950s. Despite this, the probability that a drug entering clinical trials will eventually reach the market has hardly improved in the intervening years.
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atelfo.github.io
11 October 2023
Founder of Terraform Industries and formerly a physicist at NASA's Jet Propulsion Laboratory; writes about energy, space and manufacturing.
29 August 2023
Technical staff at METR, where she works on threat modelling and risk assessment for loss-of-control risks from advanced AI.
16 July 2022
Astrophysicist and coffee researcher; author of The Physics of Filter Coffee and The Physics of Espresso, and writer of the Coffee ad Astra blog on brewing science and equipment.
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