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19 September
Dutch bootstrapper who builds and runs their internet startups alone — Nomads.com, Remote OK, Hoodmaps, Photo AI and Interior AI — and has written about it at levels.io since 2013. Posts as @levelsio.
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The faster you get rid of milk chocolate the better, you can slowly adapt yourself to darker and darker chocolate
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@levelsio on X x.com
17 September
Writer and academic, author of The Cult of Smart and How Elites Ate the Social Justice Movement; writes a daily newsletter on politics, education and culture.
Hosts the Lex Fridman Podcast — long, unhurried conversations with scientists, engineers and public figures. Several of the interviews quoted elsewhere on this site are episodes of it.
Here's my conversation with Andrew Scull, all about psychiatry, its long history from Freud/Jung to today, including asylums, icepick lobotomies, electroshock therapy, antidepressants, antipsychotics, and some horrific treatments that were considered mainstream where doctors injected patients with malaria, induced insulin comas, and pulled out their teeth, all in the name of curing madness. There are a lot of lessons to learn from history here. One of the most important for me is just how incredibly complex the human mind is, and how hard the task is of understanding & treating the nearly inf… Psychotherapy Related
14 September
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
12 September
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
I spoke too soon! Got about a dozen emails from bots trying to collect rewards from my bug bounty since yesterday. 4 were legitimate errors though very minor, relating to my vaccine discovery dataset. Quoting @scientificdiscovery.dev I'm having a similar experience, although have only received a few emails like this so far. Some are so stingy about tokens that they don't start trying to check the work unless I confirm it's eligible for a reward. Related
Writes The Diff, a newsletter on inflections in finance and tech read by hedge fund managers, founders and VCs. Previously worked in finance at SAC Capital/Point72.
10 September
Computer science professor who works on fast data processing; co-author of the simdjson parser and a weekly blogger about software performance since 2004.
I approve this message. I have already lashed out at AI doomers, and I will keep doing so. I am not going to take your totalitarian culture. I am not taking your degrowth ideology. We are moving forward. We are building. Will there be risks? Sure. But you know what? Your risk of death grows exponentially as you age. You will die sooner than you think. There is no risk-free future, for any of us. We might face a madman with nukes or whatever else. Let us build. Let us have power AIs and spaceships. Let us reject abstract fears and shallow spiritual emergencies. Quoting @Dan_Jeffries1 Not only I am tired of these wild AI speculations of impeding doom from self important people: I resent them. I actively resent people proposing to crash the economy or proposing authoritarian control over my life and other people's lives with idiotic and dangerous ideas like chip control or bans o… Related
Former L8 engineer at Meta, Microsoft and Atlassian, now writing and building solo on agentic engineering. Writes Kun's Field Notes and posts a lot about AI coding agents on X.
more and more people are discovering the great combo of herdr + firstmate. it's such a good feeling that i wish more folks could discover sooner letting a single agent babysit all your sessions is so clearly the next level experience we're all heading towards Quoting @arthurcd btw, thank you @kunchenguid. FirstMate is very impressive! Related
Programmer, writer and musician; author of the Learn Code the Hard Way books and of Mongrel, the Ruby web server.
I got the Shingles vaccine a little while ago and it's starting to look like a very good decision. Large studies repeatedly show it reduces dementia and now it's even linked to reduce cardiovascular disease. If you can get it, definitely do it. science.org
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29 August
Founder and CEO of Social Capital, a venture firm; co-host of the All-In podcast and an early Facebook executive. Writes an annual letter and a weekly newsletter on markets and technology.
28 August
Zurich-based value investor who ran the Aquamarine Fund from 1997 to 2025 and wrote The Education of a Value Investor. He hosts the VALUEx gathering in Klosters and publishes a podcast and newsletter.
I'm in a clinical trial for a brain cancer vaccine. Last month I sat down with the two men who invented it. Michael Ciesielski and Robert Fenstermaker. The idea is a vaccine called SurVaxM. It teaches the immune system to recognise survivin, a protein that helps cancer cells refuse to die. Glioblastoma is full of it. Fifteen years to get it from a Buffalo lab into patients. Related
26 August
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
x.com I wrote about the Moderna melanoma cancer vaccine news briefly for our weekly round up Related
Bluesky I wrote about the Moderna cancer vaccine news briefly for our weekly round up abundanceandgrowth.org
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Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
25 August
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
24 August
Co-founder of Microsoft and of the Gates Foundation. Writes Gates Notes on global health, energy and climate, and on whatever they have been reading.
Short Dr. Lina Finda is making sure African voices are at the center of malaria conversations. Related
21 August
Co-founder of Microsoft and of the Gates Foundation. Writes Gates Notes on global health, energy and climate, and on whatever they have been reading.
Short What Suriname can teach us about ending malaria. Related
20 August
Co-founder of Microsoft and of the Gates Foundation. Writes Gates Notes on global health, energy and climate, and on whatever they have been reading.
Short A solution from the 1960s could be key to ending malaria Related
19 August
Co-founder of Microsoft and of the Gates Foundation. Writes Gates Notes on global health, energy and climate, and on whatever they have been reading.
Short A child dies from malaria nearly every minute. We have the tools to change that. Related
18 August
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
14 August
Graphic designer and type designer, who created the original Macintosh icons and typefaces at Apple from 1982 and has since designed interface graphics for NeXT, Microsoft, Facebook and Pinterest.
Their words
But again, too much detail. It would have had a much longer lifespan if I had just stopped and made it simpler.
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10 August
Swedish designer and programmer. Designed early Spotify, worked at Facebook and Figma, and created the Inter typeface.
It’s so wild how good image and video models are getting. It’s not hard to see how in a decade (or sooner) the meaning of images you see has completely changed meaning. It makes me curious about the idea of cryptographically proving that an image was actually “captured” (recording of photon emission.) bfl.ai
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7 August
Co-founded Neuralink and founded Science Corp, which is building a retinal implant; writes about neural interfaces and biology.
28 July
American software engineer; worked on code-server at Coder and teaches TypeScript and open-source contribution. Publishes at joeprevite.com.
having a healthy body and a healthy mind should never be sold as "sacrificing family time" if anything, prioritizing your health means you'll be more present with your family because your mind will be sharper and you'll have more energy the sooner you realize this, the sooner you'll motivation shows up on its own energy Related
10 June
Co-founder and chief executive of Meta Platforms, the company he started as Facebook in 2004.
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I mean, I'm optimistic it'll be sooner. I mean, I think that the thing that's complicated is that it's a dynamic system, right? So, if you fix something, there will obviously be future things that you need to work on.
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17 April
Emeritus Professor of Statistics at the University of Cambridge, former president of the Royal Statistical Society, and author of The Art of Statistics.
Delighted to see the Covid Inquiry used one of our Winton Centre graphics in their vaccine report (p 215). But they chose the 'medium' exposure (February), rather than the more relevant 'low' exposure (March). I think this is misleading. Related
11 March
Programmer and essayist who has worked at Amazon, Google, Grab and Sourcegraph. Best known for the long-form essays collected as Stevey's Drunken Blog Rants and Stevey's Blog Rants.
11 February
Genomics researcher and writer on science, biotech and the culture of research.
2 August 2025
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
30 July 2025
Writes Useful Fictions on agency and how to get better at things; a former appellate lawyer and the top-ranked woman in professional poker in 2017.
27 July 2025
Founder of WP Engine and Smart Bear; writes A Smart Bear, long essays on strategy, pricing and how startups actually fail.
29 May 2025
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
14 April 2025
Economist at the Hoover Institution; wrote The Fiscal Theory of the Price Level and blogs as The Grumpy Economist.
3 February 2025
Machine-learning researcher on open language models; writes the Interconnects newsletter and the RLHF Book, after leading post-training at Ai2.
Their words
The more progress that AI makes or the higher the derivative of AI progress is, especially because NVIDIA's in the best place, the higher the derivative is, the sooner the market's going to be bigger and expanding and NVIDIA's the only one that does everything reliably right now.
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Founder and chief analyst of SemiAnalysis; reports on semiconductor supply chains, AI datacentre economics and what the chip export controls actually do.
Their words
But really the software engineering agents I think can be done faster sooner than any other agent because it is a verifiable domain. You can always unit test or compile, and there's many different regions of it can inspect the whole code base at once, which no engineer really can.
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10 September 2023
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
14 December 2022
Marketing author and daily blogger; founder of the altMBA and the Akimbo workshops, and author of books including Purple Cow and This Is Marketing.
30 March 2020
Co-founder and CEO of OpenAI; previously president of Y Combinator.
Please Fund More Science Experts on the COVID-19 pandemic seem to think there are three ways out—that is, for life, health, and the economy to return roughly to normal. Either we get a vaccine good enough that R0 for the world goes below 1, a g…
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