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18 September
Programmer and writer; co-founder of Stack Overflow and Discourse, and author of the Coding Horror blog, which he has written since 2004.
Dr. Betsy and I were on the Center for Effective Philanthropy podcast with Phil -- great fun and hopefully delivered the message givingdoneright.org
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14 September
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
12 September
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
I spoke too soon! Got about a dozen emails from bots trying to collect rewards from my bug bounty since yesterday. 4 were legitimate errors though very minor, relating to my vaccine discovery dataset. Quoting @scientificdiscovery.dev I'm having a similar experience, although have only received a few emails like this so far. Some are so stingy about tokens that they don't start trying to check the work unless I confirm it's eligible for a reward. Related
10 September
Programmer, writer and musician; author of the Learn Code the Hard Way books and of Mongrel, the Ruby web server.
I got the Shingles vaccine a little while ago and it's starting to look like a very good decision. Large studies repeatedly show it reduces dementia and now it's even linked to reduce cardiovascular disease. If you can get it, definitely do it. science.org
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9 September
Economist and Nobel laureate. Wrote a New York Times column for 25 years until December 2024 and now publishes several times a week on Substack.
3 September
Creator of the Keras deep-learning library and the ARC-AGI benchmark.
Side note: when we released ARC-AGI-3 in March, and frontier models scored <1% on it, a few Singularitarian poasters took it as a personal insult, and got very worked up about it. They argued the benchmark was fundamentally broken, that it could not even be solved by the smartest humans, that the max reachable score was actually 40%, etc. We had to deal with a torrent of insults and hate poasts since because we had released an unsaturated benchmark. As it turns out, the benchmark is perfectly calibrated. It is straightforward for a human to score 100% if they do better than average people – a… Quoting @fchollet Any smart human giving it real effort should score >90% on ARC-AGI-3 ARC-AGI benchmarks Related
29 August
Founder and CEO of Social Capital, a venture firm; co-host of the All-In podcast and an early Facebook executive. Writes an annual letter and a weekly newsletter on markets and technology.
28 August
Zurich-based value investor who ran the Aquamarine Fund from 1997 to 2025 and wrote The Education of a Value Investor. He hosts the VALUEx gathering in Klosters and publishes a podcast and newsletter.
I'm in a clinical trial for a brain cancer vaccine. Last month I sat down with the two men who invented it. Michael Ciesielski and Robert Fenstermaker. The idea is a vaccine called SurVaxM. It teaches the immune system to recognise survivin, a protein that helps cancer cells refuse to die. Glioblastoma is full of it. Fifteen years to get it from a Buffalo lab into patients. Related
26 August
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
x.com I wrote about the Moderna melanoma cancer vaccine news briefly for our weekly round up Related
Bluesky I wrote about the Moderna cancer vaccine news briefly for our weekly round up abundanceandgrowth.org
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Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
25 August
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
18 August
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
US science and technology adviser to the president, director of the White House Office of Science and Technology Policy; previously US chief technology officer and chief operating officer of Scale AI.
America government
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Over time that has sort of inverted completely. The private sector plus philanthropy now do about 70% of R&D and the and the government only does about 30.
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7 August
Author of Recoding America; founded Code for America and was US deputy chief technology officer from 2013 to 2014. Writes Eating Policy on why governments cannot do what they decide to do.
19 June
Author of Recoding America; founded Code for America and was US deputy chief technology officer from 2013 to 2014. Writes Eating Policy on why governments cannot do what they decide to do.
10 June
Co-founder and chief executive of Meta Platforms, the company he started as Facebook in 2004.
startups
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I think part of the theory is like if you're building tools that are this complicated, you kind of want to have a 10 to 15 year time horizon on on building out these efforts.
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17 April
Emeritus Professor of Statistics at the University of Cambridge, former president of the Royal Statistical Society, and author of The Art of Statistics.
Delighted to see the Covid Inquiry used one of our Winton Centre graphics in their vaccine report (p 215). But they chose the 'medium' exposure (February), rather than the more relevant 'low' exposure (March). I think this is misleading. Related
5 April
Author of Recoding America; founded Code for America and was US deputy chief technology officer from 2013 to 2014. Writes Eating Policy on why governments cannot do what they decide to do.
11 February
Genomics researcher and writer on science, biotech and the culture of research.
10 November 2025
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
Hiring scientists to give away money At Open Philanthropy, we have given away $600 million in biomedical research since 2016. That funding has supported the work of thousands of scientists across hundreds of universities, nonprofits, and companies around t…
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3 August 2025
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
20 September 2024
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
Effective nonprofits The most striking fact about philanthropy to me is how little money rich people give away. It is well known that we all die, and that leaving overwhelming wealth to your children can make their lives worse not better, s…
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20 December 2023
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
10 September 2023
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
30 March 2020
Co-founder and CEO of OpenAI; previously president of Y Combinator.
Please Fund More Science Experts on the COVID-19 pandemic seem to think there are three ways out—that is, for life, health, and the economy to return roughly to normal. Either we get a vaccine good enough that R0 for the world goes below 1, a g…
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