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Testing Fractional doses of COVID-19 Vaccines
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18 September
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
17 September
Author and clean-energy analyst who writes on solar cost curves.
Interesting 'RSI' data. However, it tells us nothing about the extent to which Claude is actually accelerating the pace of progress on AI. In the Mythos 5.1 system card Anthropic stated that AI tools progress had been essential to maintaining their current rate of progress. Quoting @AnthropicAI AI systems are getting more powerful, and they're increasingly being used to build the next version of themselves. We want to illuminate that progress for the public. Today, we're sharing three measurements that help track AI development: 1. How much AI R&D is done by AI. 2. How well AI agents are… Anthropic Related
Writes The Diff, a newsletter on inflections in finance and tech read by hedge fund managers, founders and VCs. Previously worked in finance at SAC Capital/Point72.
14 September
Political scientist writing Drezner's World on international relations, American politics and the marketplace of ideas; author of The Ideas Industry.
13 September
Writes Don't Worry About the Vase, a near-daily account of what is happening in AI and what they think it means. Former Magic: the Gathering pro and trader; unusually willing to put a number on a belief and to grade their own past calls.
8 September
Product designer and entrepreneur; author of Mobile First and Web Form Design; formerly a product director at Google; now building AI products.
1. many professionals will feel this if they haven't yet. 2. model capabilities keep accelerating (that's GPT-6 Astra) on the bottom of the chart. Quoting @polynoamial It can be hard to “feel the AGI” until you see an AI surpass you in a domain you care deeply about. This week, many mathematicians and physicists at @OpenAI had their Lee Sedol moment seeing this model solve, in minutes, open problems they’d struggled with for years. Related
7 September
Economist at Brown; writes ParentData and the books Expecting Better and Cribsheet, reading the evidence behind pregnancy and parenting advice.
30 August
Mathematician at UCLA, working mainly in harmonic analysis and partial differential equations. Writes What's new, a long-running blog on their research, open problems and expository notes.
In my recent ICM talk, I displayed a diagram of the life cycle of an individual problem, from an open problem all the way to a definitive solution, with a key point being that AI tools have been far more effective at accelerating some portions of this cycle than others. A point which I made verbally in the talk, but not in the image, was that the definitive solutions to problems also formed the base for subsequent progress in the field, both by suggesting new key problems to work on, and to supply new techniques to tackle these problems. I therefore enclose a further evolution of the diagram… Related
26 August
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
24 August
Co-founder and head of policy at Anthropic; writes Import AI, a weekly newsletter reading the week's AI research, and was OpenAI's policy director before that.
20 August
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
(Almost) everything you'd want to know about cancer vaccines can be heard in this great @owl_posting podcast episode from June, feat @iskander @BenjaminGVincen. Highly recommended! owlposting.com
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19 August
Writer and podcaster; co-author of Abundance with Ezra Klein, a staff writer at The Atlantic from 2008 to 2025, and host of the Plain English podcast.
11 August
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
26 July
Co-founder of NVIDIA and, as of 2026, its chief executive; the company designs the GPUs most large AI models are trained on.
24 May
Cardiologist and founder of the Scripps Research Translational Institute; writes Ground Truths on biomedical research, and wrote Super Agers and Deep Medicine.
11 March
Investment researcher and engineer who runs Lyn Alden Investment Strategy, writing on macroeconomics, currency systems and equity analysis.
9 February
Author of The Simple Path to Wealth and of the jlcollinsnh.com stock series on index-fund investing.
14 November 2025
Professor of economics at George Mason University and Bartley J. Madden Chair at the Mercatus Center. Co-writes the blog Marginal Revolution and co-authors the textbook Modern Principles of Economics with Tyler Cowen.
30 October 2025
Professor of Cognitive and Computational Neuroscience at the University of Sussex, co-director of the Sussex Centre for Consciousness Science, and author of Being You: A New Science of Consciousness.
21 September 2025
Co-founder of Sundial; former vice president of product design at Facebook; author of The Making of a Manager; writes The Looking Glass.
Their words
I think that managing change, it's always been manager's job to manage change and there's always the chaos of what's going on. I just think the rate of change is accelerating and we've seen that over the last couple of decades.
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15 August 2025
Founder of Terraform Industries and formerly a physicist at NASA's Jet Propulsion Laboratory; writes about energy, space and manufacturing.
solar
Their words
It is not only the case that solar adoption, production, price decreases are continuing. They're accelerating. And the rate that they're accelerating is still accelerating.
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11 July 2025
Co-founder of Microsoft and of the Gates Foundation. Writes Gates Notes on global health, energy and climate, and on whatever they have been reading.
Thanks to vaccines, fewer children are dying from preventable diseases around the world. Cutting funding for them would reverse that progress and put millions of children in danger. Related
3 June 2025
Co-founder of Microsoft and of the Gates Foundation. Writes Gates Notes on global health, energy and climate, and on whatever they have been reading.
It’s always an honor to partner with incredible Nigerian healthcare workers, midwives, researchers, innovators, and changemakers—like @NcpwdOfficial and Wheelchairs for Nigeria's Chief Ayuba Gufwanm, a polio survivor who has spent his life raising awareness, delivering mobility aids, and championing vaccines. People like him make me hopeful that, despite the odds and obstacles, we can #EndPolio for good. Thank you H.E. President @officialABAT for this recognition. Quoting @officialABAT Today, I conferred the Nigerian National Honour of Commander of the Federal Republic (CFR) on Mr Bill Gates @BillGates in recognition of his decades-long commitment to improving lives through interventions in global health & polio eradication, education, digital innovation, and agricultural develop… Related
22 December 2024
Astrophysicist at the University of Rochester; works on the search for life elsewhere and wrote The Little Book of Aliens and Light of the Stars.
Their words
So, we could be fooled into thinking like, "Oh, technology's going to go on forever, we're always going to find new advances." As opposed to sometimes things just flatten out for a long time. So, you have to be careful about that bias that we have living in this time of great acceleration.
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11 June 2024
Runs global health R&D at Open Philanthropy; writes about the science and medicine that could exist and does not.
30 October 2023
Professor of economics at George Mason University and Bartley J. Madden Chair at the Mercatus Center. Co-writes the blog Marginal Revolution and co-authors the textbook Modern Principles of Economics with Tyler Cowen.
20 March 2023
Researcher and science writer. Co-founder and editor at Works in Progress magazine, formerly a researcher at Our World in Data, and author of the Scientific Discovery newsletter on science, global health and medical innovation.
1 December 2022
Professor of economics at George Mason University and Bartley J. Madden Chair at the Mercatus Center. Co-writes the blog Marginal Revolution and co-authors the textbook Modern Principles of Economics with Tyler Cowen.
8 July 2022
Aeronautical engineer and former fighter pilot; analyses aircraft design and airline economics at Leeham News.
Their words
All propulsion systems are air pumps, and they work more efficiently if they accelerate a large mass of air to a small overspeed than vice versa.
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16 June 2020
Co-founder and CEO of OpenAI; previously president of Y Combinator.
Project Covalence Almost every company and non-profit working on COVID-19 that I offered to help asked for support with clinical trials—for companies focusing on developing novel drugs, vaccines, and diagnostics, rapidly spinning up tria…
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