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Jason Cohen
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Strategic choices: When both options are good
accepting painful choosing
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17 September
Entrepreneur and founder of Blueprint. Publishes a detailed, freely available longevity protocol documenting the food, supplements, devices and measurements he uses on himself.
We were surprised yesterday to learn that Kate was being asked to fill her vagina with ultrasound gel. The MRI was to characterize her endometriosis. A disease where endometrial tissue develops outside the uterus and grows. It's a gnarly and painful disease with serious health complications. It affects 1 in 10 women and currently takes on average 6.6 years to diagnose. We hustled and diagnosed Kate's endometriosis in 42 days via four speciality different tests (blood, MRI, salvia, transvaginal ultrasound). The fastest and most comprehensive ever, I think. We are doing this MRI because we have… Quoting @_katetolo I had to fill my vagina with ultrasound gel yesterday for an MRI... I had no idea this was a protocol for measuring endometriosis! how cool It's a technique called vaginal opacification... the vagina is normally a collapsed space, and on an MRI, collapsed walls are hard to tell apart from the tissu… Related
Writer on habits and decision-making; author of Atomic Habits and the 3-2-1 newsletter, and publisher of long-running book recommendation lists.
When choosing a new habit many people seem to ask themselves, "What can I do on my best days?" The trick is to ask, "What can I stick to even on my worst days?" Start small. Master the art of showing up. Scale up when you have the time, energy, and interest. energy Related
Economist and journalist; Financial Times columnist as The Undercover Economist, author of How to Make the World Add Up, and presenter of the Cautionary Tales podcast.
15 September
Creator of Flask and Jinja. Writes about software at lucumr.pocoo.org.
Their words
Pick Pulley to encourage competition to Carta. End up with Carta anyways.
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@mitsuhiko on X x.com
14 September
Entrepreneur and founder of Blueprint. Publishes a detailed, freely available longevity protocol documenting the food, supplements, devices and measurements he uses on himself.
I don't trust anyone's AI risk assessment. I don't think we know what awaits us. Given that, I'm choosing to be optimistic, betting an existence more extraordinary than we can imagine sits on the other side and it's worth fighting for. Related
13 September
Founder and chief executive of Replit. Previously an engineer at Facebook and Codecademy. Writes essays on programming, philosophy and entrepreneurship at amasad.me.
It was painful to see so many users being priced out of AI coding for a while. But now it’s free to build again! Quoting @Kyrannio Replit introducing free mode is the best thing they have ever done, but even if you are not using free mode, you are really getting a screaming great deal to develop with at present. Development costs everywhere are going to go up as the newer models come out, but I genuinely can't recommend Replit… Related
12 September
Co-founder of Modem and a founding engineer at Sentry, where he went on to be VP of Engineering. Co-author of Third-party JavaScript, and co-host of the State of Agentic Coding podcast with Armin Ronacher.
It took writing a programming book, speaking at 20+ confs, leading eng at a billion-dollar startup, having some OSS projects people use, getting invited on podcasts, starting a company, hanging out with smart / successful people who seemed to think I knew what I was doing … … before accepting maybe it wasn’t all a fluke Quoting @threepointone you don’t understand, i’m the world’s best imposter, absolutely world class imposter skills, a lifetime of developing them to be so convincing, i’ve somehow accumulated promotions, references, a career, and a body of work purely as supporting evidence for the bit. startups Related
10 September
Former L8 engineer at Meta, Microsoft and Atlassian, now writing and building solo on agentic engineering. Writes Kun's Field Notes and posts a lot about AI coding agents on X.
want to hear an interesting strategy story between meta and apple? 10 years ago i was at meta, and worked on a lot of product features that had to ship to iOS, and they all had to go through a painful apple review where anything could get cut apple back then developed a clear strategy where they used “privacy” as the angle to gain user trust and win against competition a clear example was the “ask app not to track” dialog which controls ads targeting - they made every 3p app go through that scary dialog which heavily implies to the user that they should obviously click “do not track” you migh… Related
Founded PSPDFKit in 2011 and ran it for a decade. Came back from a break to work on AI agents — the OpenClaw project, and OpenAI, joined in February 2026. Writes at steipete.me.
Their words
Duplicating logic is no longer painful. Abstractions still are.
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@steipete on X x.com
Writer of the newsletter bookbear express, on psychology, relationships, non-attachment and taste; based in San Francisco.
4 September
Director of institutional asset management at Ritholtz Wealth Management. Writes the A Wealth of Common Sense blog and co-hosts the Animal Spirits podcast with Michael Batnick.
Good question about having a mid-life crisis w/your investments It's harder to sit through stock market losses w/a bigger portfolio The next stock market crash will be a lot more painful for a new group of wealthier investors w/more $$$ at stake Related
1 September
Epidemiologist; founded Your Local Epidemiologist in March 2020 to translate public-health science, and consults for organisations including the CDC.
22 August
Founder and former CEO of Zynga, the social-games company behind FarmVille, Zynga Poker and Words with Friends; says he founded ten companies in all, and wrote Life at the Speed of Play.
Its painful that a decade ago i supported chuck schumer. Hes willing to support the worst people so his party can get power. no matter what. Jews like him and Bernie led the Jewish council in the Warsaw Ghetto and convinced thousands to get on trains peacefully. Quoting @NYPostOpinion Democrats need to stop whitewashing Abdul El-Sayed’s extremist hate Related
18 August
US science and technology adviser to the president, director of the White House Office of Science and Technology Policy; previously US chief technology officer and chief operating officer of Scale AI.
government
Their words
I think it can be a slog, it can be bureaucratic, it can be painful, but when the when the outcome actually happens and you deliver the result, there is no place where you can have a bigger impact on on this country.
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youtube.com
17 August
Founder and former CEO of Zynga, the social-games company behind FarmVille, Zynga Poker and Words with Friends; says he founded ten companies in all, and wrote Life at the Speed of Play.
Hallelujah!! Cuban’s Ro argument was painful legitimizing of a corrupt socialist policy. Govt seizure isnt ever ok. Quoting @theobjectivist This so-called defense of the founders by Cuban is worse than Ro Khanna's direct assault, because it is the assault's enabler, as their exchange below illustrates. Watch the sequence. Mark's first reply argued only mechanics. The founders are cash poor, the banks will not lend, capital will flee. N… Related
11 August
Chief scientist at Redwood Research, where he works on technical AI safety and AI control.
AI alignment
Their words
we are making a trade-off where because we don't have very good alignment technology. We are going to like make an alien mind with its own values and then gamble on that to some extent rather than doing this other approach of making like a tool that pursues individual user intention.
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youtube.com
9 August
Coffee consultant and author of books on espresso, roasting and brewing, including The Professional Barista's Handbook and The Coffee Roaster's Companion; writes about brewing gear and roast control at scottrao.com.
30 July
Chief Scientist at Google DeepMind and Google Research, at Google since 1999, where he co-created MapReduce, Bigtable, TensorFlow and the TPU.
23 July
Physician focused on longevity; wrote Outlive and hosts The Drive.
14 July
Programmer and technology writer known for his long Mac OS X reviews at Ars Technica; co-hosts the Accidental Tech Podcast and Hypercritical.
A few years ago, I commissioned a drawing of my Destiny character from an amazing artist, "EmilyMeganX" on Instagram. She’s currently accepting new commissions. Message her on Instagram if you’re interested: https://www.instagram.com/stories/emilymeganxart/3941019007574408844 You can see my Destiny character picture here: https://www.instagram.com/p/CLAB-iwpPnZ/?igsh=MWRscnpncGVldmpveA== You can even watch a time-lapse of her creating it: https://www.youtube.com/watch?v=Qu9S-iuiqr4 More videos here: youtube.com
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13 July
Front-end developer and writer; co-founder of CodePen, founder of CSS-Tricks, and co-host of the ShopTalk Show podcast.
Choosing Movies Almost surely, if you totaled up the number of hours of movie watching I’ve done and the hours of TV show watching I’ve done, TV dwarves movies.... chriscoyier.net
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7 July
Game designer and programmer, co-founder of id Software and co-creator of Doom, Quake and Wolfenstein 3D. Now runs Romero Games in Galway, Ireland.
I’m so sorry for everyone at id Software affected by these layoffs. I know what it feels like to leave id while id goes on. It’s a strange and painful thing to step away from a place that holds so much of your work, friendships and history. The people at id have done a great job moving that legacy forward. DOOM, Quake, and Wolfenstein are not easy names to carry on, especially in today’s industry. The last few games showed real care, skill and respect for what those worlds mean to people. A note on digital preservation: id's history is critically important to the history of games. I’ve preser… Related
1 July
Freelance climate and energy analyst in Oslo, writing on Europe, the US and Australia; worked in the Australian renewables industry before that.
Google
Their words
Both hide the fact the company is simply choosing the climate-wrecking road, consciously.
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ketanjoshi.co
Programmer; wrote Extreme Programming Explained and Test-Driven Development, signed the Agile Manifesto, and writes Tidy First?.
Their words
It's when you have this rapid alternation between I do a thing, I learn a thing, I do a thing, I learn a thing, I do a thing, I learn a thing. That's where TDD is really powerful. But it's not a moral decision. It's a practical decision.
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youtube.com
30 June
Mathematician and maker of the 3Blue1Brown YouTube channel, which explains mathematics through animation. Creator of the open-source Manim animation library and founder of the Summer of Math Exposition.
From one piece
Grant Sanderson (@3blue1brown) – AI disproved a famous math conjecture. Now what?
2 beliefs, in the piece's order there
Their words
I feel like a relevant insight in learning was um recognizing that like who matters more than what. So, like advice to any college student when they're choosing what courses to take. Uh, care a little bit less about your pre-existing interests because they're kind of arbitrary right now. and care a little bit more about whether like the person teaching it is a good educator and someone you resonate with.
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youtube.com
Their words
Know where the money is coming from. Know where you plug into that. And like if you're just asking those questions, you're actually already like steps ahead of all of the other like fledgling perspective mathematicians.
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youtube.com
28 June
Machine learning engineer and consultant focused on RAG and retrieval systems. He writes about applied AI engineering at jxnl.co and is the author of the instructor library.
4 June
Canadian bootstrapper and writer on small software businesses. Co-founder of the podcast hosting company Transistor.fm and author of the book Marketing for Developers.
2 June
Founder and former CEO of Zynga, the social-games company behind FarmVille, Zynga Poker and Words with Friends; says he founded ten companies in all, and wrote Life at the Speed of Play.
Their words
I think that a practice like the book of life, what it's done for me and I think it could do for a lot of people is just be strategic about your life. Like be thoughtful about like I like say what would your future self thank you for doing this year. We can be strategic, hold ourselves accountable and and force ourselves to make some tougher decisions.
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youtube.com
26 May
Professor at Wharton studying how people actually use AI, and author of Co-Intelligence. Writes One Useful Thing, where the claims are dated and testable because the thing they describe keeps changing under them.
Demographer; writes on fertility, marriage and population, and directs the Pro-Family Initiative at the Institute for Family Studies.
Their words
It just is marriage. Turkish fertility started falling super fast after 2013 because Turkish marriage rates started falling super fast after 2013.
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lymanstone.substack.com
25 May
Clinical psychologist and clinical professor of psychiatry at UCSF. His 2010 meta-analysis established psychodynamic therapy as an evidence-based treatment; he has argued ever since that "evidence-based therapy" is used as a marketing term.
24 May
Co-founder and CEO of Every. Writes the Chain of Thought column about working with AI tools and hosts the podcast AI & I.
Their words
And I think that Cursor has at least so far more distinctly chosen a lane. Like they're more distinctly choosing to be a for programmers. And that may limit how far they get in here.
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youtube.com
Organizational psychologist and professor at the Wharton School. Author of Give and Take, Originals, Think Again and Hidden Potential, host of the Re:Thinking podcast, and writer of the GRANTED newsletter.
Their words
Emotion regulation is not about controlling what you feel. It's about choosing how you respond.
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adamgrant.substack.com
18 May
Writer of the newsletter bookbear express, on psychology, relationships, non-attachment and taste; based in San Francisco.
24 April
Freelance web developer and instructor. Author of the Dive Into Docker course; writes tutorials on Docker, deployment and development environments at nickjanetakis.com.
15 April
Product designer and entrepreneur; author of Mobile First and Web Form Design; formerly a product director at Google; now building AI products.
The New Designer/Developer Collaboration There's lots of ways to build a website. Most of them involve designers working in one tool, developers working in another, and a painful handoff process somewhere in between. We recently used Intent to design, build an…
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2 April
Co-founder of Ethereum. Publishes long essays on mechanism design, governance and what cryptography is for, and returns to earlier positions to say which parts they no longer hold.
Their words
The way that I use this daemon is that I run it on NixOS as a service, accepting requests on port 6000.
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vitalik.eth.limo
11 March
American game designer and director, for nineteen years at Blizzard as a World of Warcraft quest designer and then game director of Overwatch; now runs the independent studio Kintsugiyama.
Their words
I don’t think executives who take off and work 40-hour weeks should be telling anybody to stay late. I think that’s wrong and immoral. But to me as an individual, as long as I’m not telling other people to do it, my life’s work is my passion and I want to do it as much as possible.
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youtube.com
1 January
Founder and CEO of SaaStr, the B2B software community and events business, and a SaaS investor who previously co-founded EchoSign and sold it to Adobe.
Their words
because you have to train them because it takes a month, the world's best software with no help training you is not one 99% of people should buy.
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youtube.com
Co-founder and CEO of Anthropic; previously VP of research at OpenAI.
19 December 2025
American author of The Subtle Art of Not Giving a F*ck and Everything Is F*cked. Writes essays and book reviews at markmanson.net.
18 November 2025
Author of Shape Up; formerly head of strategy at Basecamp, where he worked on product design for seventeen years; now runs Felt Presence.
30 September 2025
Founder of Telegram, and before it of VK.
Their words
I believe this is the right answer. We're often being manipulated by politicians, by corporate leaders to make a choice from two suboptimal options. And then when we are forced to make this choice and we make this choice, it's almost as if it's something that we have to assume responsibility for. I don't think we should be buying into that.
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youtube.com
3 August 2025
Philosopher at Oxford; co-founded effective altruism and 80,000 Hours, wrote Doing Good Better and What We Owe the Future, and now works on what a good future would actually contain.
8 July 2025
Mathematician at UCLA, working mainly in harmonic analysis and partial differential equations. Writes What's new, a long-running blog on their research, open problems and expository notes.
The #SalemPrize for 2025 is now accepting nominations until September 15th. www.ias.edu/math/activit... (I am the chair of the Scientific Committee for the prize.) A bit more information in my blog post on this: terrytao.wordpress.com
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14 April 2025
Economist at the Hoover Institution; wrote The Fiscal Theory of the Price Level and blogs as The Grumpy Economist.
13 March 2025
Programmer and writer; co-wrote The Rust Programming Language and worked on Rust's documentation for years.
Choosing Languages I tried to write this post yesterday, but I didn’t like my approach there. Last night, I had a conversation with one of my best friends about it, and he encouraged me to write this, but in a different way. I think this…
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16 January 2025
Engineer and writer on machine-learning systems; author of Designing Machine Learning Systems and AI Engineering. "I work to bring AI into production. I write about AI system design."
Their words
This is perhaps one of the first painful lessons anyone who has built an AI product quickly learns. It's easy to build a demo, but hard to build a product.
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huyenchip.com
25 October 2024
Non-fiction writer, podcaster and occasional TV host. Author of thirteen books including The Ghost Map, Where Good Ideas Come From and Extra Life, host of the PBS series How We Got To Now, and author of the Adjacent Possible newsletter on innovation.
21 August 2024
Clinical psychologist, EMDR consultant and yoga teacher in Boulder, Colorado. Author of The Complex PTSD Workbook and EMDR Therapy and Somatic Psychology; writes on trauma, attachment and the nervous system.
20 August 2024
Economist at the Hoover Institution; wrote The Fiscal Theory of the Price Level and blogs as The Grumpy Economist.
29 June 2024
Gwern Recommends
29 Jun 2024
Pseudonymous essayist. Writes at gwern.net on AI scaling, statistics, genetics and long-running internet research, with heavy citation and a habit of revising old essays in place rather than leaving them wrong.
Their words
Overall, required viewing for any Winehouse fan and of general psychiatric interest; possibly too painful to watch for others.
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gwern.net
21 December 2023
Journalist and author writing on politics, liberalism and ideas; a contributor to Quillette and co-author of a book on Christopher Hitchens.
9 November 2023
Founded SpaceX in 2002, joined Tesla's board in 2004 and became its chief executive in 2008; later founded Neuralink, The Boring Company and xAI. Bought Twitter in 2022 and renamed it X, where he now posts many times a day.
Their words
So generally, I think we obviously want to prioritize civilizational risks over things that are painful and tragic on a local level, but not civilizational.
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youtube.com
15 October 2023
Founder of OpenStreetMap, the collaborative map of the world; later worked on mapping at Microsoft and Telenav.
Their words
It's important to look around you for solutions instead of accepting the current unavailability of options.
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Orbitals stevecoast.com
4 May 2023
Founder of OpenStreetMap, the collaborative map of the world; later worked on mapping at Microsoft and Telenav.
1 May 2023
Family therapist and founder of Relational Life Therapy. Author of I Don't Want to Talk About It, How Can I Get Through to You? and Us; argues that Western individualism is what makes couples' work hard.
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What is a korrent?
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