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Physician focused on longevity; wrote Outlive and hosts The Drive.

• Can semaglutide slow aging?

  A new study found that semaglutide extended median lifespan and improved several measures of aging in female mice—but the headline requires careful interpretation.

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Co-creator of Django and creator of Datasette; writes daily at simonwillison.net.

• Gemini Live audio

  Tool: Gemini Live audio Google released Gemini 3.8 Live and 3.8 Live Extended Thinking today - two new speech-to-speech models that are a similar shape to OpenAI's GPT-Live family. I pointed GPT-6 Astra Extra High at th…

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Writer and teacher on productivity and personal knowledge management. Author of Building a Second Brain and founder of Forte Labs, which runs the course of the same name.

• Two people who take folders too seriously are back with an extended cut

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Non-fiction writer, podcaster and occasional TV host. Author of thirteen books including The Ghost Map, Where Good Ideas Come From and Extra Life, host of the PBS series How We Got To Now, and author of the Adjacent Possible newsletter on innovation.

• I've added @sapinker's Sense of Style to all my notebooks with writing projects, asking for a Pinker edit with each draft. I don't always agree with every suggestion but it's invariably productive and stimulating advice. Plus if you're in the US, you can get a free copy of the book, which you can both read and use as an on-demand editor in @Gemini_Notebook. There are twenty other great titles in the promotion as well, though it's a limited time offer, and you can only choose one book. (And yes, Google is paying for the books so authors/publishers will be compensated!) Full list and details he…

  play.google.com

  Quoting@sapinker"Expert intelligence" - new feature of Gemini that allows buyers of an ebook to apply the knowledge in the book to their own projects. In this case, the advice in my writing style manual, The Sense of Style, is applied to a draft of the user's writing. I checked it out and it's really good -- the a…

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• This week at @Gemini_Notebook, we're featuring two notebooks built around a pair of recent popular advice books, starting with @ericries' instant classic, The Lean Startup. Add Eric's book to any notebook, and it's like having him as your personal coach.

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Founded Bridgewater Associates in 1975 and led it until stepping back from control in 2022. Author of Principles, The Changing World Order and How Countries Go Broke; publishes economic analysis at economicprinciples.org.

• Both inside and outside of any organization, there are some people who will intentionally cause the organization harm. If these enemies are within your organization, you need to call them out to resolve this conflict through the organization's system for achieving such resolutions, because working with enemies within your "extended family" will undermine you and the "family." If the enemies are outside your organization and will use the information to harm you, of course don't share it. #principleoftheday

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Non-fiction writer, podcaster and occasional TV host. Author of thirteen books including The Ghost Map, Where Good Ideas Come From and Extra Life, host of the PBS series How We Got To Now, and author of the Adjacent Possible newsletter on innovation.

• Also, the new @NotebookLM research agent has the full context of the project you're working on—current sources, chat history, etc—so you can do nuanced research prompts like: "given everything we've reviewed so far, what topics are we missing? Find me sources on those topics."
  Quoting@joshwoodwardThe new killer NotebookLM feature: easily being able to expand your search beyond your own source files Then, with today's update, you can also make new output formats: PDFs, DOCX, XLSX, PPTX, charts, etc. We want NotebookLM to keep helping you do better research

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Non-fiction writer, podcaster and occasional TV host. Author of thirteen books including The Ghost Map, Where Good Ideas Come From and Extra Life, host of the PBS series How We Got To Now, and author of the Adjacent Possible newsletter on innovation.

• The most significant update to @NotebookLM in the three years since we launched. I’ve been using it for past two months and it is absolutely transformative for research. Rolling out to Ultra users today, support for more tiers to come.
  Quoting@Gemini_NotebookIntroducing a more powerful NotebookLM 🚀 Massive upgrades deliver agentic capabilities in chat, more advanced reasoning, and a suite of new output formats. Tackling complex, multi-step research problems has never been easier. Rolling out now to Google AI Ultra subscribers.

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Non-fiction writer, podcaster and occasional TV host. Author of thirteen books including The Ghost Map, Where Good Ideas Come From and Extra Life, host of the PBS series How We Got To Now, and author of the Adjacent Possible newsletter on innovation.

• We've been publishing "complete works" featured notebooks @NotebookLM since our original Shakespeare collection, as public resources for scholars/students. But our new Complete Sherlock Holmes has a very cool twist: it's also a playable text adventure!

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Software engineer at PlanetScale and creator of the vim-go plugin. Writes at arslan.io about Go, tooling, industrial design and books.

• Midori MD Notebooks

  Over the past months, I gathered all sorts of notebooks. Not all notebooks are meant to be used for the same task. Some are for scratching random bits, some are good for journaling, and some are nice for sketching. For…

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Investment researcher and engineer who runs Lyn Alden Investment Strategy, writing on macroeconomics, currency systems and equity analysis.

• Why Most Cryptocurrencies Won’t Accrue Value

  December 2025 For many years now, I’ve been bullish on bitcoin, and continue to be, but have not extended that view toward any other cryptocurrency. That decision continues to hold up well. Since I first recommended it…

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Creator of the Keras deep-learning library and the ARC-AGI benchmark.

• deep-learning-with-python-notebooks — Jupyter notebooks for the code samples of the book "Deep Learning with Python"

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Non-fiction writer, podcaster and occasional TV host. Author of thirteen books including The Ghost Map, Where Good Ideas Come From and Extra Life, host of the PBS series How We Got To Now, and author of the Adjacent Possible newsletter on innovation.

• Listening To The Algorithm

  Thoughts on a new feature at NotebookLM that turns your sources into an extended audio conversation.

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Member of technical staff at Anthropic. He has led ML/AI teams at Amazon, Alibaba and Lazada, and writes about LLMs, recommender systems and engineering at eugeneyan.com.

• poc-docker-template — Simple template showing how to set up docker for reproducible data science with Jupyter notebooks.

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Writer and consultant on technology, organizations and history; founded the blog Ribbonfarm and now writes the Contraptions newsletter.

• New post about monoliths. Won’t lie, it’s partly an extended excuse to use the monorail meme.

  open.substack.com

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Senior economist at the Foundation for American Innovation; writes Second Best, and was the Niskanen Center's director of social policy before that.

• How did human civilization get off the ground?

  Language, norms, and "the extended mind"

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