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Saloni Dattani x.com
Most people have never heard of siRNA, but it’s going to change the face of medicine. https://t.co/RLP1pxuICA Much drug development today involves developing chemicals to fit into proteins and block them. But this almost never turns out as planned: many drug candidates get broken down in the body, interfere with other proteins and cause toxic side effects, or fail to be absorbed at all. The majority of proteins are considered undruggable, because they lack a pocket for drugs to bind, or they are ‘intrinsically disordered’, without coherent structure. What if, instead of trying to block the pr…
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