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Writer and author of All the Wrong Moves; his newsletter covers meditation, relationships and creativity, and he co-runs a perfume line.

• Our readingkorrents.com

  Meditation is more powerful than psychedelic drugs, not milder as commonly assumed.

  Their words

  The moment when you realize that you thought drugs were powerful and meditation was mild, but you now realize the opposite is true.

  Average moments of a long-term meditatorsashachapin.substack.com

Essayist; writes Astral Codex Ten, previously Slate Star Codex.

• Our readingkorrents.com

  For psychiatric disorders driven by amygdala hyperactivity, elective amygdalectomy should be offered and covered by health insurance instead of lifelong therapy and medication.

  Psychotherapy

  Their words

  If you suffer from amygdala hyperactivity that gives you one of the aforementioned psychiatric disorders, I think that not only should you be offered elective amygdalectomy, but your health insurance should be glad to pay for it (especially if done via ultramodern very safe radiosurgery) one time, rather than for a lifetime supply of more expensive, less effective talk therapies and medications.

  Absurd Adventure And Amygdalectomy Advocacyastralcodexten.com

Programmer and teacher; writes on software, learning and the web, and makes the Coding Blocks video course.

• Readrcmnd.app

  The Psychedelic Explorer's Guide: Safe, Therapeutic, and Sacred Journeys

  Their words

  This is a fascinating topic, and there’s a lot of BS floating around it. This book is one of the good ones.

  rakhim.org

Physician focused on longevity; wrote Outlive and hosts The Drive.

• Our readingkorrents.com

  Population studies can never show that short sleep shortens life, because illness both disturbs sleep and shortens life.

  Their words

  Population-level studies will keep struggling to prove that short sleep shortens life, because they are structurally unable to separate cause from symptom—and the genetic tools meant to overcome this limitation inherit a different fatal flaw.

  Does losing sleep mean losing lifespan?peterattiamd.com

Economic historian at Columbia; writes Chartbook on economics, geopolitics and history, and wrote Crashed and The Deluge.

• Our readingkorrents.com

  The talk of history 'returning' to Europe is a symptom of disorientation among its elites, not evidence of a new realism.

  Europe

  Their words

  Rather they are the sign of disorientation, disillusionment and despair.

  Chartbook 452 Europe's Machiavellian moment?adamtooze.substack.com

Genomics researcher and writer on science, biotech and the culture of research.

• Our readingkorrents.com

  Manufacturing and batch-release requirements, not biology, are what kill most promising cell and gene therapies.

  Psychotherapy

  Their words

  Excessive manufacturing requirements are a pervasive problem, especially in the field of cell and gene therapy and they are killing countless of promising medicines before they ever reach patients.

  writingruxandrabio.com

Co-founder and chief executive of Meta Platforms, the company he started as Facebook in 2004.

• Our readingkorrents.com

  The right unit of study is a system like inflammation rather than a named disease — understand the system and others can build the therapies.

  Their words

  rather than studying the specific diseases we think that by trying to understand inflammation more broadly that will make it so that other companies that can then use these tools can work on specific therapies.

  youtube.com

Entrepreneur and founder of Blueprint. Publishes a detailed, freely available longevity protocol documenting the food, supplements, devices and measurements he uses on himself.

• Our readingkorrents.com

  The health results people attribute to expensive exotic therapies come from a small number of ordinary habits done without exception.

  Their words

  Habits and not expensive, exotic therapies.

  Bryan's Protocolprotocol.bryanjohnson.com

Co-founder and chief executive of Sierra, chairman of the board of OpenAI, and formerly co-chief executive of Salesforce and chief technology officer of Facebook.

• Our readingkorrents.com

  Even generalised superintelligence will change society more slowly than the AGI community expects, because intelligence is not the only rate limiter.

  AGIAI alignment

  Their words

  I don't think all parts of the economy can absorb intelligence equally. So let's just say we develop fairly generalized super intelligence. I always use the analogy like you can invent a lot of drugs, but if clinical trials still take a long time, you're not necessarily going to get new therapies rapidly.

  youtube.com

Psychiatrist and clinical assistant professor at Case Western Reserve University. Writes Psychiatry at the Margins on the philosophical and scientific arguments inside psychiatry and the psy-sciences.

• Likedrcmnd.app

  Psychedelic Alpha

  Their words

  Josh Hardman at Psychedelic Alpha provided a detailed live account of the advisory committee meeting, which I found very helpful in developing a more granular sense of how the meeting unfolded without having to watch it myself.

  psychiatrymargins.com