Vinay Prasad

Everything, newest first — across every channel. Their profile → · Subscribe

Sources

All topics AIPoliticsMind & health

22 October

Vinay PrasadKorrents 22 Oct

From one piece Vinay Prasad’s Observations and Thoughts 3 beliefs, in the piece's order there

korrents.com
The history of the platform and class and the success rate of the platform and class matters.

Their words

The history of the platform and class and success rate of the platform and class matters.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
A doctor who concludes a new drug must have helped because they have never seen such good responses with chemotherapy alone needs more education.

education

Their words

If you have a doctor who says "I've never seen responses this good with chemo alone, ergo new drug must have helped" That doctor needs more education - or should be recruited as your kol depending on your goal.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
It is impossible to determine the specific contribution of a new drug when it is used in combination with a tried and true backbone like chemotherapy.

Their words

If you use your novel drug with a tried and true backbone- new drug + chemo- it is impossible to know what <new drug> adds.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com

19 October

Vinay PrasadKorrents 19 Oct

From one piece Vinay Prasad’s Observations and Thoughts 2 beliefs, in the piece's order there

korrents.com
As model complexity grows, it is very likely that AI will perform even better.

Their words

As model complexity grows, it is very likely that AI will do even better.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
AI models are currently biased towards the liberal epicenters that developed them and favor liberal answers.

Their words

AI models are heavily biased towards the liberal epicenters that have developed them, and favor liberal answers.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com

15 October

Vinay PrasadKorrents 15 Oct

From one piece Vinay Prasad’s Observations and Thoughts 3 beliefs, in the piece's order there

korrents.com
The human genome is a moving, living molecule with 3 dimensional interactions that are scarcely understood, rather than being like letters in a book.

Their words

DNA is a moving, living molecule with 3 dimensional interactions we can scarcely understand. It is nothing like letters in a book.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
The analogy of the human genome being like letters in a book has done a lot of damage.

Their words

Ultimately, the idea that the human genome is like the letters in a book that tells you how to build and run a person- that analogy has done a lot of damage.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
For healthy people or those with common conditions, genomic knowledge has little to no practical value.

Their words

Yet, Brian is correct that for healthy people (or those with common conditions, e.g. HTN) the answer is: genomic knowledge has little to no practical value.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com

10 October

Vinay PrasadKorrents 10 Oct

From one piece Vinay Prasad’s Observations and Thoughts 3 beliefs, in the piece's order there

korrents.com
If AI generates a cancer cure that passes a phase 3 randomized control trial despite no one understanding its mechanism, patients will accept it.

Their words

If AI generates a cancer combination cure that no one understands, but passes a phase 3 randomized control trial, there's not a single cancer patient on Earth who would say no thank you.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
Human understanding of how the human body works is extremely limited.

Their words

We have a much deeper understanding than we did a hundred years ago, but we don't know if we have understood 5% or 50% or .05%. . We don't even know what we don't know.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
If a cancer treatment passes a phase 3 clinical trial but its mechanism of action is not understood, patients and doctors will still want to use it.

Psychotherapy

Their words

If a phase 3 clinical trial is positive, as Tao postulates, but humans do not understand the mechanism of action that would be level one evidence to administer a therapy. Every cancer patient on Earth would want it. Every doctor would give it.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com

9 October

Vinay PrasadKorrents 9 Oct

From one piece Vinay Prasad’s Observations and Thoughts 3 beliefs, in the piece's order there

korrents.com
A randomized study comparing day zero hepatitis B vaccination to delayed vaccination for low-risk neonates would be imminently important in the United States.

America

Their words

Such a randomized study would be imminently important in the United States, where this issue is heavily debated, and neither side has gold standard evidence, but the zealotry side uses bizarre arguments.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
Some people believe they know what works based on mechanistic science and low quality observational studies.

Their words

These are people who believe that they know what works based on mechanistic science and low quality observational studies.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
Many trials intended to inform US practice are unethical because they use control arms that are no longer the standard of care in the US.

Their words

Many trials meant to inform the US practice are unethical because the control arm is something we have not done in the US for quite some time- a standard that was already beaten.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com

6 October

Vinay PrasadKorrents 6 Oct

From one piece Vinay Prasad’s Observations and Thoughts 3 beliefs, in the piece's order there

korrents.com
Nobel winners are smart and also lucky.

Their words

Nobel winners aren't the smartest or best they were smart and also lucky

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
Which discoveries matter is ultimately subjective.

Their words

My point is just which discoveries matter is ultimately subjective.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com
korrents.com
The Nobel prizes miss the mark.

Their words

It's no secret that I think the Nobel prizes misses the mark.

Vinay Prasad’s Observations and Thoughtsdrvinayprasad.com

1 October

Vinay PrasadKorrents 1 Oct

korrents.com
Current systems are ill-equipped to learn from post-market data.

Their words

Our current systems are ill-equipped to learn from post-market data.

Sensible Medicinesensible-med.com

What is a korrent?

A korrent is a belief a person has stated in their own words: one sentence stating the claim, backed by a quote and a source, kept at korrents.com.

Under a name here, the quoted block is what they actually said. The korrent beneath it is the claim those words support, in korrents' wording — tap it to see the record, its source, and who else holds it.

Nobody here wrote their own korrents. They are compiled from public statements, and a person can change their mind, which is recorded too.

About the English under a post

Some people here publish in a language other than English. Where they do, this site shows a machine translation beneath the post, in this typeface — the site's own, not theirs.

The post itself is never changed, moved or hidden: what is set in the serif above is exactly what the person published, and it is what to quote them on. A translation can be wrong in ways that matter, especially about tone.

Only the post's own words are translated. A quoted post, a linked article and a belief on korrents.com are left in their original language.