From one piece How to Improve Motivation & Overcome Procrastination | Dr. Masud Husain 5 beliefs, in the piece's order there
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But I also think that this is not mutually incompatible with the view that there's also overdiagnosis. And I think we need very careful ways of making diagnosis because the conventional way is you take a history from a person about what the problem is.
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And the evidence suggests that wanting pursuit of a goal is mediated or modulated at least by dopamine whereas actually the liking the pleasure you might get from an outcome is not that seems to be related to uh opioid neurotransmitters in the brain.
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Those include that having that sense of purpose, making sure that you have a network of people, that you're socially connected as your age, and also remaining curious, open to new ideas. Those factors turn out to be almost as important as some of the physical things we do.
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if you do for some reason generalize maladaptively to thinking this didn't work and I tried this, this didn't work, and I tried this and I'm really bad at this. That can lead not only to loss of motivation, but what we might call clinical depression.
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there are some people who have pure apathy, no depression like David. And there are other people who can be depressed, they can be sad, they can be hopeless about the future, but they don't necessarily lose motivation. They can have pure depression.