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Their words
I think it’s good that the system identified the mechanisms that it did, but I don’t think that the paper does enough to point out that none of these ideas are without precedent - in some cases, a lot of precedent.
Derek Lowe
Everything, newest first — across every channel. Their profile →
Hiding
27 May
14 October 2024
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korrents.com
There are few clear-cut cases in biopharma today where buying an AI system is obviously worth it.Their words
At the moment, there are in fact not very many slam-dunk gotta-get-me-some-of-that-AI decisions out there in our business.
19 September 2024
From one piece AI and Biology 2 beliefs, in the piece's order there
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Their words
I predict (with confidence bordering on arrogance) that whatever machine-learning progress can be made will correlate extremely closely with the quality of the data around any given problem
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Their words
So for these reasons, I (unfortunately) do not expect any big AI-driven breakthroughs in biological understanding any time soon.
13 May 2024
From one piece AI Drugs So Far 2 beliefs, in the piece's order there
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korrents.com
A compound's AI origin story is not by itself a reason to expect it to do better in the clinic.Their words
For now, I am not convinced that issuing press releases about your compounds that talk about their discovery through AI techniques is sufficient to expect greater things from them.
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korrents.com
The drugs advertised as having AI-discovered targets are aimed at targets people already knew about.Their words
What you will see is that in almost every case, these targets were already known to be implicated in the disease under investigation.
25 May 2023
From one piece AI and the Hard Stuff 2 beliefs, in the piece's order there
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Their words
But we do not have enough data and we do not have enough insight to use AI/ML to pick better targets that have a higher chance of succeeding in the clinic.
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Their words
There are no existing AI/ML systems that mitigate clinical failure risks due to target choice or toxicology.
4 February 2020
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Their words
As generative drug analoging grows in importance, it's going to be crucial for people to make the entire training set available in detail when such work is published.
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